Restylane Defyne

What is Restylane Defyne?

Restylane Defyne is a hyaluronic acid-based dermal filler that smoothens and reduces moderate to severe laugh lines, i.e., the facial folds around the nose and mouth. Defyne is similar to Refyne, except it treats moderate to severe facial folds (not mild folds). It’s produced using a special XpresHAn Technology that makes the hyaluronic gel resemble the natural HA found in your skin, ensuring naturalized results that allow you to emote freely.

How does Restylane Defyne Work?

Facial folds, creases, and wrinkles occur due to the gradual loss of collagen, elastin, and hyaluronic acid from your skin. Hyaluronic acid is the primary component in most dermal fillers, but it’s also a naturally-occurring gel found in the human body. HA particles are responsible for your skin’s youthful suppleness and fullness. Restylane Defyne injects HA particles into the facial tissues with moderate to severe laugh lines to fill them out and reduce their prominence.

Restylane Defyne Treats…

Moderate to severe laugh lines, i.e., nasolabial folds around the corners of your nose and the marionette lines running down from the corners of your mouth.

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Benefits of Restylane Defyne

  • Non-surgical procedure
  • No pain or discomfort
  • Quick in-and-out procedure
  • Immediate results
  • Perfect for severe laugh lines
  • Advanced manufacturing process
  • Doesn’t affect your ability to emote
  • No downtime

You’re a Candidate if You…

  • Have severe nasolabial folds and marionette lines.
  • Are over 21 years of age.
  • Aren’t allergic to hyaluronic acid or lidocaine.
  • Don’t have a history of excessive scarring.
  • Don’t have bleeding disorders.
  • Aren’t taking blood-thinning medications.
  • Aren’t pregnant or nursing.

Restylane Defyne Highlights

  • Type: Hyaluronic acid filler
  • Treats: Moderate to severe laugh lines
  • Duration: 30-60 minutes
  • Downtime: None
  • Onset: Immediate
  • Longevity: up to 12 months
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Restylane Defyne Treatment Overview

Your cosmetic treatment starts with a private consultation with our providers. They review your medical history, examine your facial skin, and discuss your cosmetic expectations to determine if you’re a viable candidate for the procedure. If not, they recommend the ideal treatment to meet your goals. And if you’re a viable candidate, they personalize the ideal treatment plan.

The procedure

The cosmetic provider will cleanse your skin before the procedure. Restylane Defyne includes an anesthetic component called lidocaine, which numbs your skin upon contact, so an additional numbing cream isn’t necessary. The provider will mark the treatment areas on your skin and deliver Defyne with the utmost precision using ultrafine needles.


You can resume your daily activities as soon as you leave the medical spa, though you should avoid strenuous and vigorous physical activities. You might experience swelling, redness, itching, irritation, and other side effects around the injection points for a few days, but not severe enough to keep you from work.

Restylane Defyne Results

Restylane Defyne produces immediate results — your laugh lines will look a lot softer than before. However, you’ll truly appreciate the results once the side effects dissipate. The results last for up to 12 months with optimal treatment, following which you’ll need maintenance treatments.


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